Rajiv Gandhi University of Health Sciences
Keynote: Clinico haematological profile of hypochromic anemia in adults of age group 18-59 years of age: An observational study
Time : 10:00
Dr. Somil Singhal has completed his Bachelor Of Medicine and Surgery ( MBBS) at the age of 25 years of age from Beijing Medical University, China and Post Doctoral Studies in Doctor Of Medicine In Pathology from Rajiv Gandhi University Of Health Sciences, Bangalore, India. Currently he is working as Senior Consultant Pathologist in the Pathology Departrment at Kriti Scanning and diagnostic center, Allahabad, India. He has attended various Conferences, CME’s and published Case studies , Dessertation in reputed journals like IJLSSR, Index Copernicus, Poland Journal Of Dermatology and is the life member of Indian Medical Association and Allahabad Medical Association. Besides this he had worked as a Ex. resident in AIIMS Trauma Center in the department of emergency medicine, Ex. Cardiac resident at Fortis Hospital Okhla, Delhi , E. Senior Resident in ARMC Solapur , Maharashtra, Ex. Senior Resident in Maharaja Agrasen Gruop Of hospitals , New Delhi, India and besides this attended various ITO and blood bank camps for service to the society.
Background: Hypochromic anemia in adults is a complex problem owing to variations in various haematological parameters. many studies in india and abroad had evaluated the causes and its appropriateness. in spite of this , there is diagnostic dilemma in diagnosing the appropriate cause of hypochromic anemiaâ€Ÿs. hence, this necessity need to take up the study on haematological profile on hypochromic anemia.
Objectives: The aim of the study was to perform haematological investigations required for diagnosing hypochromic anemia, to estimate the iron status of bone marrow aspirations and to assess which type of haemoglobin is responsible for causing hypochromic anemia by using haemoglobin electrophoresis.
Methods: 100 cases diagnosed with hypochromic anemia on peripheral blood smear were evaluated during one and half year study at department of pathology, s. nijalingappa medical college and hsk hospital, bagalkot, karnataka. other relevant investigations like bone marrow aspiration study, bone marrow biopsy, biochemical investigations were performed. conditions associated with hypochromic anemia were studied and categorized. haemoglobin electrophoresis was performed to evaluate the cause of hypochromic anemia.
Results: Majority of cases were females as compared to males in a age group of 18 – 38 years of age with most common sign and symptom being pallor followed by fever and anorexia. the most common category of diagnosis among these cases was inadequate dietary intake and infections. 61 % cases showed lymphocytosis followed by neutrophilia and eosinophilia. the most frequent peripheral blood smear picture was dimorphic type in 39 % cases followed by pancytopenia in 33 % cases. bone marrow iron grade being 3 + in 41 % cases. haemoglobin electrophoresis showed hba2 > 3.5 % in 2 % cases suggestive of beta thalassemia trait.
Conclusion: Correlation of morphology of peripheral blood smear , bone marrow aspiration, biopsy with rbcs indices and special techniques ; complete iron profile along with serum ferritin levels and hb electrophoresis proved highly valuable in distinguishing the various sub types of hypochromic anemia.